Study record managers: refer to the Data Element Definitions if submitting registration or results information. Drug: Placebo Solution for injection, Subcutaneous injection in the abdomen, upper thigh or upper arm. Drug: Dupilumab Solution for injection, Subcutaneous injection in the abdomen, upper thigh or upper arm. Annualized event rate was the total number of exacerbations that occurred during the treatment period divided by the total number of participant-years treated. The AQLQ comprises of 32 items in 4 domains: symptoms 12 items , activity limitation 11 items , emotional function 5 items , environmental stimuli 4 items. The 32 items of the questionnaire are averaged to produce one overall quality of life score ranging from 1 severely impaired to 7 not impaired at all. Higher scores indicate better quality of life. Participants were asked to recall how their asthma had been during the previous week and to respond to each of the five symptom questions on a 7-point scale ranged from 0 no impairment to 6 maximum impairment.
Asthma is a chronic disease that causes the airways of the lungs to swell and narrow. It leads to breathing difficulty such as wheezing, shortness of breath, chest tightness, and coughing. Asthma is caused by swelling inflammation in the airways. When an asthma attack occurs, the lining of the air passages swells and the muscles surrounding the airways become tight. This reduces the amount of air that can pass through the airway.
Asthma symptoms can be caused by breathing in substances called allergens or triggers, or by other causes.
While everyone with asthma needs to take extra precautions when this week arrives, children, senior citizens and Find out how much is left in the container and whether it’s past its expiration date. Check out my website.
Compared to mild or moderate asthma, the symptoms of severe asthma are worse and ongoing. People with severe asthma may also be at an increased risk of asthma attacks. As a friend or loved one of someone with severe asthma, you can offer continued support. With severe asthma though, you might also need to bring a nebulizer to help with difficult-to-control wheezing.
People with severe asthma are at a higher risk of an asthma attack. An asthma attack can be life-threatening.
Colleague’s E-mail is Invalid. Your message has been successfully sent to your colleague. Save my selection. For more than 24 continuing education articles related to respiratory topics, go to Nursingcenter. Up-to-date asthma care.
Asthma inpatient hospitalization and emergency department (ED) visit rates vary widely among New Jersey counties. Rates for emergency visits are highest in.
You can control your asthma! When you control your asthma, you will breathe easier, be as active as you would like, sleep well, stay out of the hospital, and be free from coughing and wheezing. Asthma is one of the most common lifelong chronic diseases. One in 13 Americans nearly 25 million lives with asthma, a disease affecting the lungs and causing repeated episodes of wheezing, breathlessness, chest tightness, and coughing.
Although asthma cannot be cured, you can control your asthma successfully to reduce and to prevent asthma attacks, also called episodes. Successful asthma management includes knowing the warning signs of an attack, avoiding things that may trigger an attack, and working with your doctor to develop your personal Asthma Action Plan. Asthma deaths have decreased over time and varied by demographic characteristics. The rate of asthma deaths decreased from 15 per million in to 10 per million in
Understanding how asthma is treated and how to live well with it will improve your quality of life. For more information about controlling your asthma symptoms, visit our asthma microsite. Asthma is a chronic lung disease that causes inflammation and narrowing of the airways.
If you have any questions about the directions, ask your health care provider. If you are using your inhaler for the first time, you need to prime it. Shake your inhaler well for 5 seconds. Remove the mouthpiece cover by squeezing gently at both sides, then pulling out. Check the mouthpiece for foreign objects. Breathe out fully exhale. Hold the inhaler up to your mouth. Place the white mouthpiece fully into your mouth and close your lips around it.
Make sure that the inhaler is upright and that the opening of the mouthpiece is pointing towards the back of your throat. Breathe in inhale deeply and slowly through your mouth. Press down firmly and fully on the top of the counter on the inhaler to release the medicine. Continue to breathe in inhale and then hold your breath for about 10 seconds, or for as long as it is comfortable.
Before you breathe out exhale , release your finger from the top of the counter.
Right or Mr. Right Now, there are plenty of dating websites and apps to find him. For people with certain health conditions or concerns, it can be hard to meet new people on traditional sites like OkCupid and Tinder because they might worry about how soon to tell their potential partners about their diagnosis. People with autism may be worried about the perceived stigma surrounding their diagnosis or just the awkwardness of telling someone about it on a non-autistic dating site, Cantu told Buzzfeed News.
Will they still like me after they find out? Both Cantu and Fitzpatrick are on the spectrum, and while there are already plenty of online communities for people with autism, the mother-daughter duo were disappointed to find that none of the website owners actually have the disorder.
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Although many people first develop asthma during childhood, asthma symptoms can occur at any time in life. This fact sheet provides general information about the nature of asthma when it appears in adults for the first time. We hope that the material helps you better understand what adult onset asthma is and how you can best manage it. Please keep in mind that this information is not meant to take the place of medical advice from your own physician.
When year-old Dorothy had the flu, it took her weeks to get over it. Afterwards, she still felt winded just doing her everyday routine. Sometimes she had tightness in her chest that made her wonder if she was starting to have heart problems. At night, she noticed it was easier to breathe propped up a little bit. Finally, she talked with her physician about her symptoms. An in-office breathing test helped determine that Dorothy had asthma and her heart was just fine. Asthma symptoms can appear at any time in life.
People can develop asthma at age 50, 60, or even later. Adults who develop asthma are said to have adult onset asthma. Unlike children who often experience intermittent asthma symptoms in response to allergy triggers or respiratory infections, adults with newly diagnosed asthma generally have persistent symptoms.
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Tobacco smoke, whether you inhale from your own cigarette or breathe in secondhand smoke, is dangerous to your health. E-cigarettes may not be much better. When you have asthma, either type can be even worse. Electronic cigarettes e-cigarettes is the name given to a group of battery-operated tobacco products that allow users to inhale aerosolized liquid e-juice that has nicotine and other substances.
The terms “e-cigarettes” and “e-cigs” are often used for electronic cigarettes, as well as for e-pens, e-pipes, e-hookah, and e-cigars. These products are also sometimes called “JUULs” after a branded e-cigarette of the same name , “vapes,” and “vape pens. E-cigarettes may not be as dangerous for the person with allergies and asthma as real cigarettes. However, the dangers of e-cigarettes on allergies and asthma are not yet known so must be taken seriously. The e-juice in e-cigarettes is not pure, and could trigger an asthma attack or worsen nasal allergy symptoms, either by the person using the e-cigarettes or even from a person breathing the “second-hand” vapor that comes from the e-cigarette.
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Patient education: Asthma and pregnancy (Beyond the Basics) This article will be updated as needed on our web site (). and other health professionals up-to-date on the latest medical findings.
COVID is a respiratory illness that can cause a dry cough and shortness of breath, so it likely comes as no surprise that it can wreak havoc on the intricate respiratory system lying inside a person’s chest. Once the virus gains entry, it begins to cause injury to a person’s airways and lungs. While anyone can get infected with the new coronavirus, some people have a higher risk of developing a more serious illness — including people with moderate-to-severe asthma.
Tim Connolly, pulmonologist at Houston Methodist. If you have moderate-to-severe asthma, here’s what you need to know about your risk of developing COVID, as well as how to reduce your risk. We’re still learning exactly what happens in a person’s body during COVID, but we do know quite a bit about how coronavirus affects a person’s lungs during infection. Interestingly, while serious illness can develop in people with moderate-to-severe asthma, it’s not as prevalent as originally anticipated.
Preliminary data suggests that people with asthma may make less of the receptor that the virus uses to invade the body, called ACE2 — making it more difficult for the virus to gain entry into the host. In addition, ongoing maintenance therapy with inhaled steroids, such as budesonide, may also confer an advantage for people with chronic lung conditions,” explains Dr.
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Respiratory syncytial virus RSV is the most common respiratory pathogen in infants and young children worldwide. Furthermore, epidemiologic evidence has been accumulating that RSV lower respiratory tract infection in infants may be linked to subsequent development of recurrent wheezing and asthma in childhood. This article reviews the epidemiological evidence linking RSV and asthma and some new hypotheses of the cellular and molecular mechanisms of post-viral airway inflammation and hyperreactivity that have been proposed to explain the epidemiologic link.
New epidemiologic studies have suggested that viral pathogens other than RSV, especially human rhinoviruses HRV , may play an important role in the inception of atopic asthma. Also, recent experimental evidence is challenging the widely accepted axiom that RSV is cleared from immunocompetent hosts within weeks from the onset of the infection. In particular, bone marrow stromal cells may be a frequent target of human RSV infection, develop structural and functional changes when infected, participate actively in the pathogenesis of the acute disease, and harbor the virus chronically allowing persistence of the infection.
RSV — and possibly other common respiratory pathogens — play an important role not only in the exacerbation, but also in the inception of asthma. The latter effect may involve the persistence of latent virus in extrapulmonary tissues, similar to what has been recently found for some bacterial species. The most immediate consequence of these discoveries is that future prophylactic and therapeutic strategies for common infections caused by viral or bacterial pathogens may have to address the coverage of remote sites of latent persistence or replication, in order to avoid chronic sequelae recurrent wheezing and asthma.
Seasonal outbreaks occur each year during the winter months throughout the world, although onset, peak, and duration of the season vary from one year to the next and are difficult to predict. In the United States and throughout the northern hemisphere, the annual epidemics usually begin in November, peaking in January or February and ending in May.
Regional variability is significant, with the sub-tropical areas like Florida showing an endemic pattern and less predictable epidemic peaks. It is estimated that each year, as many as , infants